The Lobbyist versus the people

November 17th, 2008

Or the case of Thailand compulsory licensing vs. right wing pharmaceutical lobbyists

This article was written in May 2007, revised in June 2007 and minor edits were made on 17/11/08. I decided to republish it after my attention was drawn by the Wisdom of Whores to a recent opinion piece written by Roger Bate for the New York Times. In his latest article for the NYT, Bate conflates generic and counterfeit medicine finding another occasion to held high the flag of a sometimes unscrupulous pharmaceutical industry. The text below is a rather vitriolic piece that is however well referenced and documented. Access to life saving medicine is an issue I have at heart and I am afraid I have little tolerance for fantasy or corporate interests when it comes to saving life.

On 19 September 2006, the Royal Thai Army staged a coup against the government of caretaker Prime Minister Thaksin Shinawatra. Soon after, in November, the Thai Ministry of Public Health Mongkol Na Songkhla issued a compulsory license (CL) for the first-line Aids-fighting drug Efavirenz (Sustiva/Stocrin) manufactured by Merck, sparking a row that turned in to a war when in January compulsory licenses were issues for the heart disease drug Plavix, made by Bristol-Myers Squibb and Sanofi-Aventis, and Kaletra (Aluvia) a heat-stable HIV protease inhibitor made by Abbott Laboratories.

In February, Merck agreed to lower the price for Efavirenz to 700 baht per bottle from the pre-compulsory licence price of 1,400 baht. In contrast, Abbott Laboratories opted for a punitive reaction and withdrew its applications to market new drugs in Thailand. The rippling effect of Thailand’s CL soon propagated across the developing world. In May 2007, Brazilian President Luiz Inacio Lula da Silva signed a decree to issue a CL for Efavirenz and Brazil was promptly accused of an “IP opportunism” that threatens the US private property rights.

Back in 2006, the Intellectual Property war machine of the US Pharmaceutical industry was swiftly set in motion and a huge propaganda campaign started against Thailand’s decision to use the provisions contained in the international Trade-Related Aspects of Intellectual Property Rights (TRIPS) agreement signed at Doha in 2001.

One of the advocates of the Pharmaceutical Industry is Roger Bate, a resident fellow at the American Enterprise Institute (AEI). According to his bio at the AEI, “Economist Roger Bate researches U.S. and international aid policy in Africa and the developing world, evaluating the performance and effectiveness of USAID, the World Bank, the Millennium Challenge Corporation, NGOs, as well as other aid organizations and development policy initiatives.”

Roger Bate is a distinguished academics who holds a Ph.D. in economics and an M.Phil. in land economy from the University of Cambridge (UK), an M.Sc. in environmental and resource management from the University College, London University (UK) and a B.A. in economics from the Thames Valley University (UK).

Roger Bate has been a vocal if not vociferous contributor to the dispute opposing the US pharmaceutical giant Abbott and the Thai military-led government. He published a series of opinions, articles and reports both for the AEI, in the mainstream media and for online publications, disapproving of and condemning the Thai decision to use the TRIPS provisions.

With such academic credential, one could hardly be tempted to question Roger Bate professional integrity and expertise. But on a closer look it happens that his support of the pharmaceutical industry is often rooted in half truth, misinformation, bias and sometimes plain lies.

A brief Internet search on the American Enterprise Institute reveals that the AEI is an influential, pro-business right-wing think tank founded in 1943 by Lewis H. Brown. It is funded by one of the world’s largest oil companies (ExxonMobil) and has close links with the Bush Administration.

In February 2007, the London based newspaper The Guardian revealed that scientists and economists have been offered $10,000 each by the AEI to undermine a major climate change report due to be published by the UN’s Intergovernmental Panel on Climate Change (IPCC). The AEI sent letters offering payments for articles emphasising the shortcomings of the report. Such practices shed light on what kind of “Think Tank” the AEI is.

A review of the articles written by Roger Bate on the issue of compulsory licensing reveals a regular pattern that is epitomised in The Cost of Cheap Drugs, published on June 1, 2007. Right from the start, Roger Bate showed his ability to report well documented events with inaccuracy and questionable innuendo.

“In September 2006 the former Thai government was overthrown in a largely bloodless military coup”, wrote Bate in the opening line of The Cost of Cheap Drugs of a coup that was totally bloodless. Thailand has lived through numerous coups in the last 70 years and the purpose of such innuendo is unclear if it wasn’t to question the legitimacy of a decision taken in the interest of the public by a military junta. But lest we forget, Thailand successful fight against HIV was initiated whilst a similar junta was in charge of the country in the 90s and later lost steam under the Thaksin administration.

Roger Bate often indulges in partial and biased reporting for instance when emphasizing the reaction of Dr Margaret Chan, the director of the WHO, who, he wrote “…was shocked by Thailand’s move. Back in February, when she visited Thailand, she cautioned against such hasty action.” But at the World Health Organization’s annual summit in Geneva (14-23 May 2007) where intellectual property issues were prominent a resolution on “Public Health, Innovation and Intellectual Property” was adopted in plenary session of the 60th World Health Assembly encouraging the WHO Director-General to guide the process to draw up a global strategy to remedy the problem of IP, R&D and costs of drugs and to provide technical and policy support to developing countries for that purpose. In other words to provide support to the developing world to use and apply the TRIPS Agreements.

In her closing remark the allegedly “shocked” Dr. Chan commented that she was “fully committed to this process and have noted [the WHO member’s] desire to move forward faster.” She added that “We must make a tremendous effort. We know our incentive: the prevention of large numbers of needless deaths and suffering.”

Roger Bate also often refers to the corruption pervading the Thai Government Pharmaceutical Organisation (GPO, manufacturer of the GPO-vir) quoting “Mr Jaruvan Maintake”, Auditor General at the Constitutional Court of Thailand (whose appointment to this position had been the object of a controversy). (Note : Bate most likely wanted to refer to Mrs Jaruvan Maintaka, a women whose patronym is Maintaka, but he can be excused for the difficulty to transliterate Thai names and for being unfamiliar with Thai first name even though he writes a lot about Thailand.)

Further disinformation followed when Roger Bate recalled “a 2005 study by Thailand’s Mahidol University’s faculty of medicine [that] found at least 40% and up to 59% resistance in the 300 patients investigated.” Roger Bate teamed up with another Right Wing lobbyist group USA for Innovation who ran a libelous advert in the Bangkok Post earlier in 2007. USA for Innovation executive director is Ken Adelman, who also works for Edelman Public Relations Worldwide, which counts Abbott Laboratories as one of its biggest clients. Bate and Adelman were later contradicted by Wasun Chantratita, chief of Mahidol University’s virology and molecular microbiology unit, who said in the Thai newspaper The Bagkok Post (May 12, 2007) that, “the advert that cited his study was only half-true. He said the study on drug resistance was conducted in 2000 _ two years before GPO-VIR even existed. It focused on three individual original drugs _ Nevirapine, Lamivudine (3Tc) and Stavudine (d4T) _ not GPO-VIR. GPO started to produce GPO-VIR, which combines Nevirapine, Lamivudine and Stavudine, in 2002.” Then the GPO was seeking criminal-defamation action against USA for Innovation and was seeking 1bn Baht in compensation.

Bate often insists that, “even the Global Fund to Fight AIDS, Tuberculosis and Malaria, which has arguably shown enormous tolerance of the GPO, finally withdrew financial support last August”. Little mattered that the World Bank was planning to provide Thailand with a $750,000 three-year grant aimed at providing HIV-positive people with increased access to antiretroviral drugs and help address funding issues associated with the country’s universal health care system, as well as providing training for nurses and doctors in an effort to overcome the shortage of health care personnel in the country (The Nation, February 6, 2007). (Note: See here for an update on the global Fund position towards Thailand)

But again, Bate expressed his concerns that “cheaper drugs do not make cheaper healthcare if they don’t work properly.” Of course, as pointed out by Daniel Ten Kate in the Asia Sentinel (May 10, 2007), “USA for Innovation and other propaganda groups will never cite an August 2006 World Bank study that calls for Thailand to resist Big Pharma and use compulsory licensing to reduce HIV/AIDS drug costs by up to $3.2 billion by 2025. It also won’t refer to letters of support sent to the Thai government from the World Health Organization, UNAIDS and countless NGOs, including the Clinton Foundation headed by former President Bill Clinton.”

The picture would not be complete if Bate had refrained from nursing the myth that “World Trade Organization rules have made compulsory licenses available to poor countries suffering an epidemic. But Thailand is a middle income country, and, while a case may be made for HIV, heart disease, cholesterol and leukemia are not epidemics.” This ignores the assessment made by the Associate Director of Washington College of Law’s Program on Information Justice and Intellectual Property (PIJIP) which concluded that “Thailand’s issuance of compulsory licenses for three patented medicines is legal under domestic laws and complies with WTO rules, and Abbott’s decision to withhold its new products from the Thai population violates Thai antitrust laws” but also ignores that in its 2007 Special 301 Report the “United States acknowledges a country’s ability to issue such licenses in accordance with WTO rules”.

Bate should also well know that compulsory licenses issued under the TRIPS agreement are not limited to poor countries or situation of medical emergency since the USA have been using the same TRIPS agreements for their benefit in situation hardly close to medical emergencies ranging from patent related to the Blackberry device to Toyota hybrid transmissions and material used in F-22 fighter jets. Indeed the TRIPS agreement clearly states that each member is free to determine the grounds upon which such licenses are granted.

One can only expressed bewilderment with a lobbyist’s ability to broadcast so many inconsistencies, inaccuracies, biased and one-sided reporting, and fallacies in less than 800 words. Lacks of integrity and professionalism, partisanship, or genuine professional incompetence are the choices left to the readers. One is justified having reservations about the credibility of such lobbyist to contribute meaningfully and honestly to such an important debate.

Many other are perpetuating the same myths, printing the same fallacies and misleading the public, including Bibek Debroy, a professional economist, Secretary-General of the PHD Chamber of Commerce and Industry, India, and former consultant to India’s Ministry of Finance (Obsession with lower cost leads to deadly mistake, The Bangkok Post, December 6, 2006), Philip Stevens, director of the health programme at the International Policy Network, a corporate-funded, London-based development think tank (Licensing policy fatal for HIV/Aids sufferers, The Nation, February 14, 2007), USA for innovation, the Baker & McKenzie law firm (Compulsory drug licenses violate world trade treaty, The Bangkok Post, April 23, 2007), some serious news outlets such as the Wall Street Journal, the Financial Times and some less scrupulous professional who do not check their facts.

That these people and interest groups wish to support the Pharmaceutical industry is their right, but that they do so with lies, misrepresentation and misinformation is not acceptable.

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Thailand’s ladyboys: nearly human?

November 13th, 2008
miss-soi-4
Miss Pink Competition 2006
© peripheries

In an article strangely entitled “Thailand’s lady-boys are in a class of their own, at last”, The Independent reports on the Bangkok Suan Dusit University where young male transgenders are allowed to wear make up and female uniform. It is this “at last” that is rather strange.

There is no question that Thai ladyboys deserve to be treated like any other human beings within the Thai society. In this regard Thailand is much more liberal than most western societies, though this liberalism is very much codified and not has accepting as most foreigners would like to think. But this “at last” suggests that the Suan Dusit university resolved the matter by segregating ladyboys into specific class with special needs and obligations.

I happened to live next to an annex of the Suan Dusit University near the Suan Lum Night Bazaar and to have had lunch with the students at a nearby food market (This annex is now closed). I was first surprised to see male students wearing male trousers as required by the University dress code but also heavy make up, long hair and overtly behaving like women. I got used to it and I guess this is part of the Katoey persona; as noted in the Independent article “If you want to be a woman, act like one”. They were often overdoing it but this was not the always the case as I witnessed during ladyboys’ competition.

As I am not convinced that separate toilets will facilitate the recognition of equal rights for Katoye, I am much more in favour of unisex toilet, I am not convinced that giving Katoye “a class of their own” will end discrimination against them. The evidence is in the comment of the vice-president for student affairs, Pacharee Suankaew: Katoey “can study everything on offer, except education. ‘We can’t have them teaching kindergarten children and they accept that’ and “In return, she says, the students must be ladylike.”

So long as Katoey stay in their well defined Katoey-box, it is all fine. Can this be called equal rights?

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Ageing AIDS - Forgetting Nan and Grandad

November 12th, 2008

nahof_2Earlier in September, peripheries commented on HIV amongst people over 50 and the importance of not excluding them from VCT on the basis that they were too old.

In this week’s New York Times, Karen Barrow noted that “Today, because of antiretroviral therapy and an array of drugs to treat both symptoms and side effects, AIDS has become a chronic condition to be managed, at least in the developed world. No longer is the face of AIDS emaciated and covered with lesions; Americans with the disease are stronger and healthier, their concerns fading from public view.”

According to the CDC, 29% of people living with AIDS in the U.S. are over 50 and they account for 15% of all new HIV/AIDS diagnosis in 2005. Myron Gold, 67, former fashion designer turned AIDS and gay-rights activist after being diagnoses with HIV aged 42, asked “What about people 65 and older?”, “They’re having unprotected sex, they’re using drugs.”

Nobody wants to hear about grandpa’s sex life and even less about grandma’s sex life. If it is clear that to date the Seniors are not a very attracting category of people to feel for when it comes to HIV, not as interesting as women and children, not as ignored as MSM and not as looked down on as sex workers,  they will nonetheless weight heavily on the health care system when it comes to treatment.

Though the cost of antiretroviral is expected to go down, new molecules as well as second and third line therapy will remain expensive. Treatment of HIV-related diseases will also weight in particularly in undiagnosed population, who will incidentally continue infecting other as they often consider that they are exempt from condom use. HIV also complicates the treatment of other diseases associated with ageing such as cancer.

The burden of treating an ageing but still sexually active population must be factored in the big HIV/AIDS equation before its cost overtakes the medical care system. And lest we forget, it is still time to prevent the next generation to follow in the steps of this generation.

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VCT without Treatment in Singapore

November 10th, 2008

The city-cum-state of Singapore is to implement an opt-out screening for HIV in its public hospitals. So far so good. Early detection means a better follow up, an early initiation of treatment, an opportunity to reduce further transmission, and an extended life expectancy.

singapore

“Cracked”
Tan Ngiap Heng

Many studies have found that VCT (Voluntary Counselling and Testing) is an effective strategy for facilitating the behaviour-changes necessary to an effective HIV prevention and for providing early access to care and support. But VCT is not very useful without access to treatment. This may explain why 7 out of 10 people who participated in the pilot programme opted out of the screening.

The pilot conducted at the Changi hospital identified 50 HIV positive people out of 3,000 tested, which is in sharp contrast with the 0.3 % estimated HIV prevalence in Singapore (UNFPA) but after all, people attend hospital because their health bring them there.

For the Senior Minister of State For Foreign Affairs, Dr Balaji Sadisivan. “Whatever the reasons for failing to diagnose HIV may be, this is not something our hospitals can be proud of.” Strangely enough, Dr Balaji do not seem to think that the lack of access to treatment was a sign of failure.

As Roy Chan, president of Action For AIDS, observed: “You have to give people a reason why they want to get tested….(screening)… that is not the end of the story, you still have to provide support services.”

Interestingly, Richard Bellamy, specialist registrar in infectious diseases and general internal medicine, who spent 16th months in Singapor noted that,

“The Singapore health service has a limited list of drugs which patients can be prescribed at subsidised rates. Antiretrovirals are not included, so patients must meet the full costs. Initially, I thought this burden was a sign of a cruel and insensitive government. After a few months in Singapore, however, I realised that local people place greater value on support from their families than from the State. It was wrong to judge the system with my Western values; Singaporeans would be just as shocked by many aspects of British society, such as our system of caring for elderly people. People with HIV and AIDS in Singapore accept that it is their responsibility to pay for their treatment and they constantly impressed me with their determination to do so.”

In 2005 the same Dr Balaji announced that the Health Ministry will be raising fund to help women and children infected with HIV. Another example where money is raised and assigned to intervention against evidences: HIV Prevalence amongst women is three time lower than amongst men in Singapore and in 2007, according to the Singapore Ministry of Health there was 392 HIV infected men (most ageing one) for 31 HIV-infected women. So much for the women and child.

As previously observed, we should not pit “Western Truth against Native Error”; but that should not stop us pitting native truth against native error.

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HIV Prevention: Real Woman Waits

November 6th, 2008

real-womenLack of funds and misused thereof are the two main causes of a failing HIV prevention. As noted by Emily Geminder, HIV prevention does not attract as much financial attention as a quest for an HIV treatment, and when funds are committed to prevention, they end up financing interventions that are more dogmatic than evidence-based and whose results are hardly quantifiable and rarely quantified.

This USAID-sponsored poster promoting abstinence in Zambia as part of an HIV prevention campaign is a good illustration of what William Easterly describes as “the native people of Africa” having “to acknowledge Western Truth against native error” (in The White Man’s Burden, OUP, paperback 2007, p207).

In a few words this campaign succeeds bringing to life a vision of Africa where lewd and short-sighted women succumb to the charm of powerful men driving daunting cars, putting the short term retribution of sex before their future. But thanks to the West and its (christian) values of chastity and fidelity, real women, that is women who can wait, will succeed in life and get a career (as PA). But then, do real men real (have to) wait?

Emily Geminder quoted Susan Watkins a research scientist and sociologist who has long studied the response to AIDS in rural sub-Saharan Africa:

“I think there are a lot of misconceptions about AIDS in Africa – including misconceptions among the agencies of the United Nations”. Too often, she told MediaGlobal, “depictions of gender and HIV in international and national policy documents do not reflect the reality on the ground.”

She also quoted Catherine Campbell, who has studied prevention strategies in South Africa:

“HIV prevention strategies are informed by the assumptions of Western science and policy, with insufficient assessment of whether these are appropriate for local conditions. Proposals for projects funded by overseas bodies may be written by external consultants and presented to local groups for implementation. Local people may therefore have little sense of ‘ownership’ of the proposals.”

And concluded that “In many ways, it’s the archetypal tale of modern times. Western interventions fail to accommodate the nuances and complexities of local topographies. Too often, they rely on outdated conceptions and over-simplified conclusions. Out-of-place values get in the way of real solutions.”

There are a lot questions being raised currently within the scientific community about where the money should be invested and it seems that there is a lot of questions starting to be raised regarding how prevention has been and should be conducted where it is most needed. These are interesting times that may introduce a long needed sense of accountability to intervention and therefore results on the ground.

In Thailand a survey conducted by Fritz van Griensven and colleagues found that HIV prevalence among MSM in Bangkok has increased from 17 percent in 2003 to 30 percent in 2007. In Chiang Mai, prevalence increased from 15.3 percent in 2005 to 16.9 percent last year. In Phuket, prevalence leapt from 5.5 percent in 2005 to 20 percent in 2007.

Commenting in The Nation, Chatwut Wangwon, a member of a joint Thai Public Health Ministry and US CDC program said that “The best means of preventing HIV among MSM is providing free condoms and lubricant and raising awareness about health checks to diagnose HIV early.”

Would one be vindicated asking why with such prevalence being known since 2003, prevention interventions have failed to decrease incidence amongst MSM?

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